Jefferies LLC

Cowen and Company, LLC

Piper Jaffray & Co.

520 Madison Avenue

599 Lexington Avenue

800 Nicolette Mall

New York, NY 10022

New York, New York 10022

Minneapolis, Minnesota 55402

 

May 6, 2019

 

VIA EDGAR

 

United States Securities and Exchange Commission

Division of Corporation Finance

100 F Street, N.E.

Washington, D.C. 20549

 

Re:

 

Milestone Pharmaceuticals Inc.

Acceleration Request for Registration Statement on Form S-1

File No. 333-230846

 

Dear Sir/Madam:

 

Pursuant to Rule 460 of the General Rules and Regulations under the Securities Act of 1933, as amended (the “Act”), we, as representatives of the several Underwriters, wish to advise you that approximately 935 copies of the Preliminary Prospectus included in the Registration Statement on Form S-1 were distributed during the period April 29, 2019 through the date hereof, to prospective underwriters, institutions, dealers and others.

 

We have been informed by the participating underwriters that they will comply with the requirements of Rule 15c2-8 under the Securities Exchange Act of 1934, as amended.

 

In accordance with Rule 461 of the Act, we hereby join in the request of Milestone Pharmaceuticals Inc. for acceleration of the effective date of the above-named Registration Statement so that it becomes effective at 4:00 p.m. Eastern time on May 8, 2019, or as soon thereafter as practicable.

 

[Remainder of page intentionally left blank]

 


 

 

Very truly yours,

 

 

 

 

By:

JEFFERIES LLC

 

 

 

 

By:

/s/ Matthew Kim

 

 

Name: Matthew Kim

 

 

Title: Managing Director

 

 

 

 

 

 

 

By:

COWEN AND COMPANY, LLC

 

 

 

 

By:

/s/ Chris Swindle

 

 

Name: Chris Swindle

 

 

Title: Managing Director

 

 

 

 

 

 

 

By:

PIPER JAFFRAY & CO.

 

 

 

 

By:

/s/ Chad Huber

 

 

Name: Chad Huber

 

 

Title: Managing Director

 

[Signature page to Acceleration Request Letter]

 

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